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Terbutalino [Inn-Spanish] en es it fr

Terbutalino [Inn-Spanish] Brand names, Terbutalino [Inn-Spanish] Analogs

Terbutalino [Inn-Spanish] Brand Names Mixture

  • No information avaliable

Terbutalino [Inn-Spanish] Chemical_Formula

C12H19NO3

Terbutalino [Inn-Spanish] RX_link

http://www.rxlist.com/cgi/generic3/terbutaline.htm

Terbutalino [Inn-Spanish] fda sheet

Terbutalino [Inn-Spanish] msds (material safety sheet)

Terbutalino_[Inn-Spanish] MSDS

Terbutalino [Inn-Spanish] Synthesis Reference

K. Wetterlin, L. A. Svensson, Belg. pat. 704,932; eidem, U.S. pat. 3,937,838 (1968, 1976 both to Draco)

Terbutalino [Inn-Spanish] Molecular Weight

225.284 g/mol

Terbutalino [Inn-Spanish] Melting Point

119-122 oC

Terbutalino [Inn-Spanish] H2O Solubility

213 mg/mL

Terbutalino [Inn-Spanish] State

Solid

Terbutalino [Inn-Spanish] LogP

1.567

Terbutalino [Inn-Spanish] Dosage Forms

Metered-dose (aerosol); Powder; Tablets; IV injection; Subcutaneous injection

Terbutalino [Inn-Spanish] Indication

For the prevention and reversal of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema.

Terbutalino [Inn-Spanish] Pharmacology

Terbutaline is a relatively selective beta2-adrenergic bronchodilator. The pharmacologic effects of beta adrenergic agonist drugs, including terbutaline, are at least in part attributable to stimulation through beta adrenergic receptors of intracellular adenyl cyclase, the enzyme which catalyzes the conversion of adenosine triphosphate (ATP) to cyclic- 3',5'- adenosine monophosphate (c-AMP). Increased c-AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.

Terbutalino [Inn-Spanish] Absorption

No information avaliable

Terbutalino [Inn-Spanish] side effects and Toxicity

Terbutaline Sulfate: Oral LD50(rat) = 8.7 g/kg; Oral LD50(mouse) = 205 mg/kg; Oral LD50(dog) = 1.5 g/kg; IP LD50(rat)= 220 mg/kg ; IP LD50(mouse) = 130 mg/kg; Oral LD50(rabbit) = >8 g/kg; IV LD50(mouse) = 36 mg/kg; IV LD50(dog) = 116 mg/kg; IV LD50(rabbit) = 110 mg/kg

Terbutalino [Inn-Spanish] Patient Information

Terbutalino [Inn-Spanish] Organisms Affected

Humans and other mammals